High levels of anti-human immunodeficiency virus type 1 (HIV-1) memory cytotoxic T-lymphocyte activity and low viral load are associated with lack of disease in HIV-1 …
C Rinaldo, XL Huang, ZF Fan, M Ding, L Beltz… - Journal of …, 1995 - Am Soc Microbiol
C Rinaldo, XL Huang, ZF Fan, M Ding, L Beltz, A Logar, D Panicali, G Mazzara, J Liebmann…
Journal of Virology, 1995•Am Soc MicrobiolLack of disease in long-term nonprogressors with human immunodeficiency virus type 1
(HIV-1) infection was strongly associated with very low copy numbers of HIV-1 DNA and
RNA in peripheral blood mononuclear cells and plasma and the presence of high levels of
anti-HIV-1 CD8+ memory cytotoxic T lymphocytes specific for Gag, Pol, and Env, compared
with levels present in intermediate and advanced progressors. CD8+ memory cytotoxic T
lymphocytes may have an important role in controlling HIV-1 replication and preventing …
(HIV-1) infection was strongly associated with very low copy numbers of HIV-1 DNA and
RNA in peripheral blood mononuclear cells and plasma and the presence of high levels of
anti-HIV-1 CD8+ memory cytotoxic T lymphocytes specific for Gag, Pol, and Env, compared
with levels present in intermediate and advanced progressors. CD8+ memory cytotoxic T
lymphocytes may have an important role in controlling HIV-1 replication and preventing …
Lack of disease in long-term nonprogressors with human immunodeficiency virus type 1 (HIV-1) infection was strongly associated with very low copy numbers of HIV-1 DNA and RNA in peripheral blood mononuclear cells and plasma and the presence of high levels of anti-HIV-1 CD8+ memory cytotoxic T lymphocytes specific for Gag, Pol, and Env, compared with levels present in intermediate and advanced progressors. CD8+ memory cytotoxic T lymphocytes may have an important role in controlling HIV-1 replication and preventing disease in long-term nonprogressors.
American Society for Microbiology