Alterations of the phenotype of colonic macrophages in inflammatory bowel disease
G Rogler, T Andus, E Aschenbrenner… - European journal of …, 1997 - journals.lww.com
Background: Intestinal macrophages play an important role in mucosal inflammation. In
normal colonic mucosa we recently demonstrated a unique macrophage phenotype with
attenuated immune functions. Here we present an analysis of the alterations of the
phenotype of colonic macrophages in inflammatory bowel disease (IBD). Methods: Intestinal
macrophages were isolated from biopsies of patients with IBD (n= 20). Flow cytometric triple
fluorescence analysis was applied to study CD14, CD16, CD33, HLA-DR, CD44, CD11b …
normal colonic mucosa we recently demonstrated a unique macrophage phenotype with
attenuated immune functions. Here we present an analysis of the alterations of the
phenotype of colonic macrophages in inflammatory bowel disease (IBD). Methods: Intestinal
macrophages were isolated from biopsies of patients with IBD (n= 20). Flow cytometric triple
fluorescence analysis was applied to study CD14, CD16, CD33, HLA-DR, CD44, CD11b …
