Molecular characterization of feline melanocortin 4 receptor and melanocortin 2 receptor accessory protein 2
M Habara, N Mori, Y Okada, K Kawasumi… - General and …, 2018 - Elsevier
Abstract Melanocortin 4 receptor (MC4R), which is a member of the G protein-coupled
receptor (GPCR) family, mediates regulation of energy homeostasis upon the binding of α-
melanocyte-stimulating hormone (α-MSH) in the central nervous system (CNS).
Melanocortin 2 receptor accessory protein 2 (MRAP2) modulates the function of MC4R. We
performed cDNA cloning of cat MC4R and MRAP2 and characterized their amino acid
sequences, mRNA expression patterns in cat tissues, protein–protein interactions, and …
receptor (GPCR) family, mediates regulation of energy homeostasis upon the binding of α-
melanocyte-stimulating hormone (α-MSH) in the central nervous system (CNS).
Melanocortin 2 receptor accessory protein 2 (MRAP2) modulates the function of MC4R. We
performed cDNA cloning of cat MC4R and MRAP2 and characterized their amino acid
sequences, mRNA expression patterns in cat tissues, protein–protein interactions, and …
