Integrated genomics approaches identify transcriptional mediators and epigenetic responses to Afghan desert particulate matter in small airway epithelial cells

A Gupta, SK Sasse, R Berman… - Physiological …, 2022 - journals.physiology.org
Military Deployment to Southwest Asia and Afghanistan and exposure to toxic airborne
particulates have been associated with an increased risk of developing respiratory disease,
collectively termed deployment-related respiratory diseases (DRRDs). Our knowledge about
how particulates mediate respiratory disease is limited, precluding the appropriate
recognition or management. Central to this limitation is the lack of understanding of how
exposures translate into dysregulated cell identity with dysregulated transcriptional …

[HTML][HTML] Comparative Physiological Genomics: Integrated genomics approaches identify transcriptional mediators and epigenetic responses to Afghan desert …

A Gupta, SK Sasse, R Berman, MA Gruca… - Physiological …, 2022 - ncbi.nlm.nih.gov
Abstract Military Deployment to Southwest Asia and Afghanistan and exposure to toxic
airborne particulates have been associated with an increased risk of developing respiratory
disease, collectively termed deployment-related respiratory diseases (DRRDs). Our
knowledge about how particulates mediate respiratory disease is limited, precluding the
appropriate recognition or management. Central to this limitation is the lack of
understanding of how exposures translate into dysregulated cell identity with dysregulated …