Antihistamines and azithromycin as a treatment for COVID-19 on primary health care–a retrospective observational study in elderly patients

JIM Blanco, JAA Bonilla, S Homma, K Suzuki… - Pulmonary …, 2021 - Elsevier
Abstract Background Between March and April 2020, 84 elderly patients with suspected
COVID-19 living in two nursing homes of Yepes, Toledo (Spain) were treated early with
antihistamines (dexchlorpheniramine, cetirizine or loratadine), adding azithromycin in the 25
symptomatic cases. The outcomes are retrospectively reported. The primary endpoint is the
fatality rate of COVID-19. The secondary endpoints are the hospital and ICU admission
rates. Endpoints were compared with the official Spanish rates for the elderly. The mean age …