Characterization of intercellular adhesion molecule-1 and HLA-DR expression in normal inflamed skin: Modulation by recombinant gamma interferon and tumor …
CEM Griffiths, JJ Voorhees, BJ Nickoloff - Journal of the American Academy …, 1989 - Elsevier
Lymphocytes bind to cultured keratinocytes that are treated with interferon gamma (IFN-γ)
and tumor necrosis factor (TNF). When the lymphocytes are preincubated with antibody to
lymphocyte function associated antigen—1 (LFA-1), this adherence is inhibited. Because
intercellular adhesion molecule—1 (ICAM-1) is a ligand for LFA-1, we studied the cellular
expression of ICAM-1, as well as two other IFN-γ-inducible antigens,(HLA) human
lymphocyte antigens DR and DQ, in both normal and diseased skin. The modulation of …
and tumor necrosis factor (TNF). When the lymphocytes are preincubated with antibody to
lymphocyte function associated antigen—1 (LFA-1), this adherence is inhibited. Because
intercellular adhesion molecule—1 (ICAM-1) is a ligand for LFA-1, we studied the cellular
expression of ICAM-1, as well as two other IFN-γ-inducible antigens,(HLA) human
lymphocyte antigens DR and DQ, in both normal and diseased skin. The modulation of …