A sensitive method to quantify HIV-1 antibodies in mucosal samples
M Prabhakaran, S Narpala, SF Andrews… - Journal of …, 2021 - Elsevier
Human immunodeficiency virus (HIV) remains a significant public health issue. In recent
years, passive immunization with broadly neutralizing antibodies (bNabs) is being
considered as a potentially efficacious approach for fighting HIV. One candidate that holds
great promise is represented by the CD4-binding site targeted bNab capable of neutralizing
over 90% of circulating HIV strains, VRC01. VRC01 along with its variants and clonal
relatives–VRC01-LS and VRC07-523LS are currently being evaluated as vaccines in a …
years, passive immunization with broadly neutralizing antibodies (bNabs) is being
considered as a potentially efficacious approach for fighting HIV. One candidate that holds
great promise is represented by the CD4-binding site targeted bNab capable of neutralizing
over 90% of circulating HIV strains, VRC01. VRC01 along with its variants and clonal
relatives–VRC01-LS and VRC07-523LS are currently being evaluated as vaccines in a …
