[HTML][HTML] The Sonic hedgehog pathway mediates carbamylated erythropoietin-enhanced proliferation and differentiation of adult neural progenitor cells
L Wang, ZG Zhang, SR Gregg, RL Zhang, Z Jiao… - Journal of biological …, 2007 - ASBMB
Carbamylated erythropoietin (CEPO), a well characterized erythropoietin (EPO) derivative,
does not bind to the classical EPO receptor and does not stimulate erythropoiesis. Using
neural progenitor cells derived from the subventricular zone of the adult mouse, we
investigated the effect of CEPO on neurogenesis and the associated signaling pathways in
vitro. We found that CEPO significantly increased neural progenitor cell proliferation and
promoted neural progenitor cell differentiation into neurons, which was associated with up …
does not bind to the classical EPO receptor and does not stimulate erythropoiesis. Using
neural progenitor cells derived from the subventricular zone of the adult mouse, we
investigated the effect of CEPO on neurogenesis and the associated signaling pathways in
vitro. We found that CEPO significantly increased neural progenitor cell proliferation and
promoted neural progenitor cell differentiation into neurons, which was associated with up …