The epsins define a family of proteins that interact with components of the clathrin coat and contain a new protein module
JA Rosenthal, H Chen, VI Slepnev, L Pellegrini… - Journal of Biological …, 1999 - ASBMB
Epsin (epsin 1) is an interacting partner for the EH domain-containing region of Eps15 and
has been implicated in conjunction with Eps15 in clathrin-mediated endocytosis. We report
here the characterization of a similar protein (epsin 2), which we have cloned from human
and rat brain libraries. Epsin 1 and 2 are most similar in their NH 2-terminal region, which
represents a module (epsin NH 2 terminal homology domain, ENTH domain) found in a
variety of other proteins of the data base. The multiple DPW motifs, typical of the central …
has been implicated in conjunction with Eps15 in clathrin-mediated endocytosis. We report
here the characterization of a similar protein (epsin 2), which we have cloned from human
and rat brain libraries. Epsin 1 and 2 are most similar in their NH 2-terminal region, which
represents a module (epsin NH 2 terminal homology domain, ENTH domain) found in a
variety of other proteins of the data base. The multiple DPW motifs, typical of the central …
