The aim of this study was to elucidate the expression of chemokines, their role and
regulation in bacterial corneal infection using three bacterial strains (Pseudomonas.
aeruginosa-invasive, cytotoxic and contact lens induced acute red eye strains) which have
been shown to produce three distinct patterns of corneal disease in the mouse. The
predominant chemokine expressed in response to all three strains was MIP-2. Prolonged
expression of high levels of MIP-2 was associated with increased severity of corneal …