Adenoviral vector transfection into the pulmonary epithelium after cecal ligation and puncture in rats
YG Weiss, J Tazelaar, BA Gehan… - The Journal of the …, 2001 - pubs.asahq.org
Background Adenoviral-targeted gene delivery to respiratory epithelium can augment
production of specific proteins. Therefore, it may be valuable in treating the acute respiratory
distress syndrome. The authors tested the hypothesis that adenoviral vector uptake after
cecal ligation and double puncture in rats, an animal model of the acute respiratory distress
syndrome, is higher than that observed in controls that did not undergo operation ("
nonoperated") or those that underwent a sham operation (" sham-operated"). Methods …
production of specific proteins. Therefore, it may be valuable in treating the acute respiratory
distress syndrome. The authors tested the hypothesis that adenoviral vector uptake after
cecal ligation and double puncture in rats, an animal model of the acute respiratory distress
syndrome, is higher than that observed in controls that did not undergo operation ("
nonoperated") or those that underwent a sham operation (" sham-operated"). Methods …
